| Characteristic | Details |
|---|---|
| Generic Name | Sildenafil Citrate |
| Available Dosages | 50 mg, 100 mg |
| Form | Tablet |
| Mechanism of Action | PDE5 Inhibitor |
| Onset of Action | 30-60 minutes |
| Duration | 4-6 hours |
| Learn More | |
Chemical Structure
Sildenafil Citrate, the active ingredient in Womenra, is a PDE5 inhibitor. Its chemical structure involves a pyrazolopyrimidinone core. This structure enables binding to the phosphodiesterase type 5 enzyme, critical in the regulation of blood flow in the penile area. The molecular formula is C22H30N6O4S. The distinct crystalline form of Sildenafil allows for effective absorption and onset of action.
The structural composition enhances its solubility and bioavailability. Stability in varying pH conditions supports consistent performance. This ensures that Womenra 100 mg can perform its role efficiently under physiological conditions. The fine balance in its structure is essential for its therapeutic action.
Sildenafil undergoes hepatic metabolism primarily via CYP3A4 and CYP2C9 enzymes. This metabolism results in an active metabolite that further extends its therapeutic benefits. The excretion is primarily renal, ensuring clearance from the system post-therapeutic action.
Womenra Use
Womenra is used primarily to treat erectile dysfunction (ED) in men. It facilitates an erection by increasing blood flow to the penis during sexual stimulation. It is a therapeutic breakthrough for those with ED, significantly enhancing quality of life.
The medication is typically taken orally, 30 minutes to one hour before anticipated sexual activity. The effects of Womenra 50 mg can last up to four hours, providing a sufficient window for spontaneous interaction. Physicians might adjust dosages based on efficacy and tolerability.
Consistency in timing and dosage is crucial for optimal results. Regular intake as per medical advice can lead to improved outcomes. It’s essential to consider dietary and lifestyle factors for maximum efficacy.
FDA-Approved Indications
Sildenafil 100 mg holds FDA approval for the treatment of erectile dysfunction. This approval is grounded in extensive clinical trials demonstrating significant efficacy and safety. The approval offers assurance of its benefits for intended uses.
The drug’s action focuses on enhancing the body’s natural erectile response. Through PDE5 inhibition, Womenra maintains cyclic GMP levels in the corpus cavernosum. This biochemical cascade ensures sustained blood flow and erection.
While its primary indication is ED, ongoing research explores other potential therapeutic roles. These include applications in pulmonary hypertension, though with specific formulations and dosing regimens.
Cautions with Other Medicines
Womenra has specific interactions with other pharmaceuticals. Concomitant use with nitrates poses a significant risk due to potentiated hypotensive effects. Patients on nitrates for cardiac conditions should avoid Sildenafil.
Alpha-blockers also require careful consideration. The combination can lead to symptomatic hypotension. Monitoring and dose adjustments are essential in such scenarios.
Interaction with CYP3A4 inhibitors like ketoconazole and erythromycin can alter Sildenafil metabolism. These interactions may increase systemic exposure to Sildenafil, necessitating dosage adjustments.
- Avoid alcohol as it may amplify side effects.
- Grapefruit products may influence drug levels.
- Consult healthcare providers for complete drug interaction details.
Side Effects
The common side effects include headaches, flushing, and dyspepsia. These are usually mild and transient. Most users experience minimal discomfort.
Some might encounter visual disturbances. These include changes in color perception and blurred vision. Persistent or severe symptoms warrant medical attention.
Rare but serious side effects include priapism. Prolonged erections exceeding four hours require immediate intervention. Such occurrences, although infrequent, need prompt management.
Regular monitoring helps mitigate adverse effects. Adherence to prescribed dosages reduces risk. Open communication with healthcare providers is vital for safety.
Purchase Womenra No Prescription
Womenra is available online through various platforms. These sources often offer Sildenafil 100 mg without a prescription. It’s crucial to exercise caution when purchasing medications online.
Seek reputable vendors to ensure product authenticity. Verify sources through reviews and testimonials. A reliable platform guarantees genuine medication and safe usage.
Consider the legal implications of purchasing prescription drugs without a formal prescription. This ensures compliance with regional healthcare regulations. Safety and legality must guide purchasing decisions.
Purchasing Womenra online can offer convenience. However, professional medical advice remains indispensable. This ensures optimal outcomes and minimizes risks.